Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498562 | 0.87 | SIRT1 (0.46) | SIRT1SIRT6CPB1CPB2EPHX1 | |
| SCHEMBL17722384 | 0.87 | SIRT1 (0.46) | SIRT1SIRT6CPB1CPB2EPHX1 | |
| SCHEMBL13498651 | 0.87 | EPHX1 (0.62) | SIRT1SIRT6EPHX1SIRT2SIRT3 | |
| SCHEMBL13498644 | 0.87 | EPHX1 (0.53) | SIRT1SIRT6EPHX1SIRT2SIRT3 | |
| SCHEMBL13498646 | 0.87 | EPHX1 (0.57) | SIRT1SIRT6EPHX1SIRT2SIRT3 | |
| SCHEMBL14262320 | 0.85 | SIRT1 (0.44) | SIRT1SIRT6CPB1CPB2EPHX1 | |
| SCHEMBL13780259 | 0.84 | SIRT1 (0.43) | SIRT1SIRT6CPB1CPB2EPHX1 | |
| SCHEMBL13901982 | 0.84 | CPB1 (0.46) | SIRT1SIRT6CPB1CPB2EPHX1 | |
| SCHEMBL14805675 | 0.84 | SIRT1 (0.46) | SIRT1SIRT6CPB1CPB2EPHX1 | |
| SCHEMBL13661424 | 0.84 | EPHX1 (0.45) | SIRT1SIRT6CPB1CPB2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153992-A1 | BRANCHED AND DEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE | NOF CORPORATION (JP) | 2022-05-19 | — | — | US | disclosed |