Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900081 | 0.86 | GALK1 (0.40) | CCR5OPRM1FAAHTRPV1SLC37A4 | |
| SCHEMBL3900078 | 0.86 | GALK1 (0.40) | CCR5OPRM1FAAHTRPV1SLC37A4 | |
| SCHEMBL13902230 | 0.79 | EPHX2 (0.41) | TRPV1SLC37A4CNR1EPHX2CNR2 | |
| SCHEMBL13562270 | 0.69 | TOP2A (0.44) | TRPV1EPHX2 | |
| SCHEMBL545922 | 0.68 | PTGS2 (0.45) | — | |
| SCHEMBL3915410 | 0.68 | OPRM1 (0.57) | CCR5OPRM1FAAHTRPV1 | |
| SCHEMBL3915407 | 0.68 | OPRM1 (0.57) | CCR5OPRM1FAAHTRPV1 | |
| SCHEMBL15690210 | 0.67 | HTR1A (0.56) | — | |
| SCHEMBL15690211 | 0.67 | HTR1A (0.56) | — | |
| SCHEMBL25342401 | 0.67 | PRKDC (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1681280-B1 | NOVEL PHENOL DERIVATIVES AND ANTITRYPANOSOMA PREVENTIVE/THERAPEUTIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | ARIGEN PHARMACEUTICALS INC (JP) | 2009-03-25 | — | — | EP | disclosed |