Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13902236 | 0.79 | CCR5 (0.39) | EPHX2SLC37A4TRPV1CNR1CNR2 | |
| SCHEMBL3900081 | 0.78 | GALK1 (0.40) | EPHX2SLC37A4TRPV1CNR1CNR2 | |
| SCHEMBL3900078 | 0.78 | GALK1 (0.40) | EPHX2SLC37A4TRPV1CNR1CNR2 | |
| SCHEMBL13562270 | 0.77 | TOP2A (0.44) | EPHX2TRPV1LTA4HHTR1A | |
| SCHEMBL11045083 | 0.72 | NFE2L2 (0.51) | CYP1A2CYP2D6MAPTCYP1A1CYP1B1 | |
| SCHEMBL3902678 | 0.71 | OPRM1 (0.52) | EPHX2TRPV1CYP1A2TP53CYP3A4 | |
| SCHEMBL29191117 | 0.71 | LTA4H (0.37) | EPHX2SLC37A4TRPV1LTA4HCYP1A2 | |
| SCHEMBL15690211 | 0.70 | HTR1A (0.56) | CYP1A2HPGDCYP1A1CYP1B1HTR1A | |
| SCHEMBL15690210 | 0.70 | HTR1A (0.56) | CYP1A2HPGDCYP1A1CYP1B1HTR1A | |
| SCHEMBL28075459 | 0.70 | L3MBTL1 (0.46) | MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1681280-B1 | NOVEL PHENOL DERIVATIVES AND ANTITRYPANOSOMA PREVENTIVE/THERAPEUTIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | ARIGEN PHARMACEUTICALS INC (JP) | 2009-03-25 | — | — | EP | disclosed |