Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080014 | 1.00 | KMT2A (0.47) | KMT2AMAPK1ALDH1A1TDP1MEN1 | |
| SCHEMBL9776582 | 0.88 | KMT2A (0.47) | KMT2AALDH1A1MEN1RAB9AMAPT | |
| SCHEMBL10615162 | 0.88 | KMT2A (0.47) | KMT2AALDH1A1MEN1RAB9AMAPT | |
| SCHEMBL10696970 | 0.83 | TSHR (0.46) | KMT2AMEN1 | |
| SCHEMBL13902855 | 0.83 | SMN1; SMN2 (0.44) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL10612008 | 0.82 | KCNH2 (0.43) | KMT2AMAPK1ALDH1A1TDP1MEN1 | |
| SCHEMBL10612121 | 0.81 | ITGA4 (0.41) | KMT2AALDH1A1MEN1 | |
| SCHEMBL7441323 | 0.79 | LMNA (0.51) | ALDH1A1ARMAPT | |
| SCHEMBL605143 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1TDP1MAPTL3MBTL1 | |
| SCHEMBL8873387 | 0.78 | ITGA4 (0.52) | KMT2AALDH1A1MEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005003134-A1 | A NOVEL PROCESS FOR THE PREPARATION OF CILAZAPRIL | HETERO DRUGS LIMITED (IN) | 2005-01-13 | — | — | WO | disclosed |
| WO-2005003134-A1 | A NOVEL PROCESS FOR THE PREPARATION OF CILAZAPRIL | HETERO DRUGS LIMITED (IN) | 2005-01-13 | — | — | WO | disclosed |
| US-5610153-A | ENZYME INHIBITORS; TREATMENT OF VASCULAR PROLIFERATION DISORDERS, STERILITY DYSFUNCTION, DYSMENORRHEA | CIBA-GEIGY CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| US-5098841-A | Reduction of 2-oxo-4-phenylbutyric acid with the enzyme D lactate dehydrogenase from staphylococcus or from bovine heart | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | disclosed |