SCHEMBL13904063

SCHEMBL13904063

C#CC[C@@H]1OC(C)(C)O[C@@H]1[C@@H](/C=C\[C@@H](C)[C@H](C)O)OCc1ccc(OC)cc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13904105 0.86 CYP3A4 (0.34) OGA
SCHEMBL13903894 0.86 CYP3A4 (0.34) OGA
SCHEMBL13904057 0.85 APLNR (0.31) —
SCHEMBL13156629 0.79 FFAR1 (0.34) —
SCHEMBL13156670 0.78 RAB9A (0.32) OGA
SCHEMBL17082369 0.73 APLNR (0.33) —
SCHEMBL12772099 0.73 APLNR (0.32) OGA
SCHEMBL15385384 0.73 — —
SCHEMBL15150406 0.73 MEN1 (0.32) OGA
SCHEMBL15150405 0.72 IDO1 (0.32) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090082313-A1 Multikinase Inhibitors for Use in the Treatment of Cancer EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-03-26 — — US disclosed
US-20090048333-A1 Zearalenone Macrolide Derivatives and Uses of the Same EISAI CO., LTD. (JP) 2009-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082313-A1 Multikinase Inhibitors for Use in the Treatment of Cancer EGFR, ERBB3, FLT3 OGA 3944/4885
US-20090048333-A1 Zearalenone Macrolide Derivatives and Uses of the Same ZDHHC20, ZYX, SLC39A3 OGA 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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