Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311737 | 0.83 | ALOX15 (0.41) | MAPTNPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL13906341 | 0.82 | CCR2 (0.41) | MAPTKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL13906287 | 0.79 | KIF11 (0.45) | KDM4ENPC1RAB9ASTK17B | |
| SCHEMBL21399420 | 0.78 | AR (0.41) | PTGS2MAPTALDH1A1HPGDAR | |
| SCHEMBL20228273 | 0.78 | AR (0.41) | PTGS2MAPTALDH1A1HPGDAR | |
| SCHEMBL12011026 | 0.76 | NFE2L2 (0.54) | PTGS2MAPTACHEARPTGS1 | |
| SCHEMBL16258105 | 0.76 | NFE2L2 (0.54) | PTGS2MAPTACHEARPTGS1 | |
| SCHEMBL265481 | 0.76 | NFE2L2 (0.54) | PTGS2MAPTACHEARPTGS1 | |
| SCHEMBL13906340 | 0.76 | AKR1C2 (0.41) | PTGS2MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL10018704 | 0.74 | NISCH (0.46) | PTGS2MAPTACHEARPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032249-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK & CO., INC. (US) | 2009-03-12 | — | — | WO | disclosed |