Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908946 | 0.91 | POLB (0.39) | KMT2ALMNATHRBCYP2C19POLB | |
| SCHEMBL13908945 | 0.82 | RNASE1 (0.32) | RNASE1CA12CA1CA2CA9 | |
| SCHEMBL5911959 | 0.81 | ADRB1 (0.38) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL5911950 | 0.81 | ADRB1 (0.38) | KMT2ALMNACA12CA1CA2 | |
| SCHEMBL13908921 | 0.80 | SMYD2 (0.33) | POLBRNASE1 | |
| SCHEMBL5912284 | 0.79 | LMNA (0.39) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL5912275 | 0.79 | LMNA (0.39) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL13908941 | 0.75 | POLB (0.49) | KMT2ACYP2C19POLBRNASE1CA1 | |
| SCHEMBL5911887 | 0.74 | SLC29A1 (0.36) | KMT2ALMNATHRBCYP2C19CA12 | |
| SCHEMBL5911894 | 0.74 | SLC29A1 (0.36) | KMT2ALMNATHRBCYP2C19CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090060836-A1 | DERIVATIVES OF 2-NITRO-1,3-IMIDAZOLE COUPLED TO AMINO ACIDS AND DEOXYRIBOSE USEFUL FOR THE DETECTION OF HYPOXIC BIOLOGICAL TISSUE | EBERHARD-KARLS-UNIVERSITAET TUBINGEN UNIVERSITAETSKLINIKUM (DE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090060836-A1 | DERIVATIVES OF 2-NITRO-1,3-IMIDAZOLE COUPLED TO AMINO ACIDS AND DEOXYRIBOSE USEFUL FOR THE DETECTION OF HYPOXIC BIOLOGICAL TISSUE | HIF1AN, HIF1A, HYOU1 | KMT2A 1183/4885LMNA 2091/4885THRB 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.