SCHEMBL1390940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1390841	0.83	NPC1 (0.43)	CA12CA2CA7CA9CA14
	SCHEMBL15159385	0.82	MAOA (0.42)	CA12CA2CA7CA9CA14
	SCHEMBL2342209	0.80	MAOA (0.53)	CA12CA2CA7CA9CA14
	SCHEMBL12640266	0.79	ALDH1A1 (0.42)	MAOAMAOBMAPTNPC1RAB9A
	SCHEMBL1257100	0.79	TP53 (0.46)	CA12CA2CA7CA9CA14
	SCHEMBL1390990	0.79	HSD17B10 (0.55)	CA12CA2CA7CA9CA14
	SCHEMBL15842408	0.77	ALDH1A1 (0.53)	CA12CA2CA7CA9CA14
	SCHEMBL8142145	0.77	HRH3 (0.44)	CA12CA2CA7CA9CA14
	SCHEMBL29846449	0.76	MAOB (0.64)	CA12CA2CA7CA9CA14
	SCHEMBL9510159	0.76	TNKS (0.59)	MAOBMAPTNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.