SCHEMBL13911027

SCHEMBL13911027

c1ccc(-c2nnc(-c3cc(-c4nnc(-c5ccccc5)c5ccccc45)c(-c4nnc(-c5ccccc5)c5ccccc45)cc3-c3nnc(-c4ccccc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.50
LMNA P02545 3/20 0.50
NPSR1 Q6W5P4 7/20 0.49
ALDH1A1 P00352 9/20 0.47
MAPT P10636 4/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
PDE5A O76074 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
CYP2C19 P33261 1/20 0.46
PDE1A P54750 1/20 0.46
PDE1B Q01064 1/20 0.46
PDE3B Q13370 1/20 0.46
PDE1C Q14123 1/20 0.46
PDE3A Q14432 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4864061 0.88 HTT (0.60) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL13911030 0.86 HTT (0.54) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL13457926 0.83 HTT (0.56) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL13911024 0.81 HTT (0.54) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL7068103 0.80 ALDH1A1 (0.53) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL580814 0.78 KMT2A (0.45) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL219856 0.76 KDM4E (0.65) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL7664718 0.76 NPSR1 (0.49) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL580414 0.76 MAPT (0.49) HTTLMNANPSR1ALDH1A1MAPT
SCHEMBL7657206 0.76 HTT (0.48) HTTLMNANPSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703300-B2 Organic electroluminescent element, display and illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2014-04-22 US disclosed
US-8703300-B2 Organic electroluminescent element, display and illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2014-04-22 US disclosed
US-20090072715-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND ILLUMINATOR KONICA MINOLTA HOLDINGS, INC. (JP) 2009-03-19 US disclosed
US-20090072715-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND ILLUMINATOR KONICA MINOLTA HOLDINGS, INC. (JP) 2009-03-19 US disclosed