Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 9/20 | 0.70 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.63 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.63 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921863 | 1.00 | KCNH3 (0.70) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13921821 | 0.99 | KCNH3 (0.68) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13921833 | 0.92 | FCGR3B (0.67) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13921832 | 0.91 | FCGR3B (0.80) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13917179 | 0.89 | FCGR3B (0.81) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13921814 | 0.89 | FCGR3B (0.77) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13921815 | 0.88 | FCGR3B (0.55) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13421097 | 0.87 | FCGR3B (0.75) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13421092 | 0.86 | FCGR3B (0.81) | KCNH3FCGR3BFCGR1AFCGR2ARECQL | |
| SCHEMBL13421089 | 0.84 | FCGR3B (0.70) | KCNH3FCGR3BFCGR1AFCGR2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075867-A1 | Triazine compounds and compositions thereof for the treatment of cancers | PROMETIC BIOSCIENCE INC. (CA) | 2009-03-19 | — | — | US | disclosed |
| US-20090068169-A1 | 2,4,6-triamino-s-triazine-based compounds which bind to the tail (fc) portion of immunoglobulins and their use | PROMETIC BIOSCIENCES INC. (CA) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068169-A1 | 2,4,6-triamino-s-triazine-based compounds which bind to the tail (fc) portion of immunoglobulins and their use | FCGR2A, FCGR3B, FCGR1A | KCNH3 1915/4885FCGR3B 2/4885FCGR1A 3/4885 |
| US-20090075867-A1 | Triazine compounds and compositions thereof for the treatment of cancers | MCTS1, TYR, BRAF | KCNH3 3451/4885FCGR3B 4723/4885FCGR1A 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.