Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926329 | 0.82 | MEN1 (0.33) | MEN1KMT2AUSP2SRCAPOBEC3A | |
| SCHEMBL13926648 | 0.73 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13926451 | 0.69 | ADRB2 (0.40) | MEN1KMT2APTGDR2NPC1RAB9A | |
| SCHEMBL3834687 | 0.64 | RAB9A (0.40) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3834682 | 0.64 | RAB9A (0.40) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL15624209 | 0.63 | APP (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL15624210 | 0.61 | APP (0.47) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13926456 | 0.60 | MEN1 (0.53) | MEN1KMT2APTGDR2NPC1RAB9A | |
| SCHEMBL22743691 | 0.60 | CHAT (0.52) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13133372 | 0.60 | RAB9A (0.57) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037325-A2 | THIOL/DISULFIDE INDOLE-DERIVED, STYRYL DYE, DYE COMPOSITION COMPRISING SAID DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |