Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.54 |
| ▸ | NPY1R | P25929 | 6/20 | 0.54 |
| ▸ | NPY2R | P49146 | 4/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715717 | 0.90 | TRPV1 (0.49) | NPY4RNPY1RNPY2RNPY5RTRPV1 | |
| SCHEMBL18867987 | 0.86 | SPHK1 (0.49) | NPY4RNPY1RNPY2RNPY5RSPHK1 | |
| SCHEMBL8768680 | 0.82 | LTA4H (0.47) | NPY4RNPY1RNPY2RNPY5RSPHK1 | |
| SCHEMBL2033471 | 0.81 | LNPEP (0.44) | NPY4RNPY1RNPY2RNPY5RSPHK1 | |
| SCHEMBL20715656 | 0.81 | LTA4H (0.58) | SPHK1GAAMAPTCRHBPCRHR2 | |
| SCHEMBL13751369 | 0.81 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RSPHK1 | |
| SCHEMBL20715888 | 0.80 | GAA (0.56) | TRPV1SPHK1GAAMAPTCRHBP | |
| Ibuprofen SCHEMBL43029 | 0.79 | PTGS1 (0.57) | NPY4RNPY1RNPY2RNPY5RTRPV1 | |
| Ibuprofen SCHEMBL43030 | 0.79 | PTGS1 (0.57) | NPY4RNPY1RNPY2RNPY5RTRPV1 | |
| SCHEMBL16572313 | 0.79 | SPHK1 (0.55) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036650-A1 | Compounds and methods for peptide synthesis | BIOGEN IDEC MA INC. | 2009-02-05 | — | — | US | disclosed |
| US-20090036650-A1 | Compounds and methods for peptide synthesis | BIOGEN IDEC MA INC. | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036650-A1 | Compounds and methods for peptide synthesis | PTMS, NPPA, DNPEP | NPY4R 761/4885NPY1R 1007/4885NPY2R 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.