Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.67 |
| ▸ | MMP1 | P03956 | 10/20 | 0.67 |
| ▸ | PGR | P06401 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13287782 | 0.93 | NR3C1 (0.69) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL11246943 | 0.91 | NR3C1 (0.69) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL20589425 | 0.88 | NR3C1 (0.67) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL7616536 | 0.88 | NR3C1 (0.67) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL8505887 | 0.88 | NR3C1 (0.67) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL7204794 | 0.86 | NR3C1 (0.68) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL7209692 | 0.85 | NR3C1 (0.70) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL7203731 | 0.85 | NR3C1 (0.70) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL7203486 | 0.84 | NR3C1 (0.66) | NR3C1MMP1PGRCYP3A4USP2 | |
| SCHEMBL11235399 | 0.84 | NR3C1 (0.81) | NR3C1MMP1PGRCYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2009-02-19 | — | — | US | disclosed |
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | MPO, EPX, NOD1 | NR3C1 237/4885MMP1 413/4885PGR 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.