Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162768 | 0.86 | CA12 (0.45) | MAPTALDH1A1MAPK1KCNQ3KCNQ2 | |
| SCHEMBL2104690 | 0.84 | RORC (0.48) | MAPTALDH1A1KCNQ3KCNQ2TAS1R3 | |
| SCHEMBL13163319 | 0.84 | ALDH1A1 (0.42) | MAPTALDH1A1MAPK1KCNQ3KCNQ2 | |
| SCHEMBL2617353 | 0.82 | KCNQ3 (0.37) | MAPTALDH1A1MAPK1KCNQ3KCNQ2 | |
| SCHEMBL14531483 | 0.82 | RORC (0.43) | MAPTALDH1A1MAPK1KCNQ3KCNQ2 | |
| SCHEMBL2104930 | 0.81 | XDH (0.49) | ALDH1A1 | |
| SCHEMBL2544970 | 0.80 | CA12 (0.56) | MAPTALDH1A1MAPK1TAS1R3TAS1R1 | |
| SCHEMBL6529701 | 0.80 | MGLL (0.49) | MAPTALDH1A1MAPK1TAS1R3TAS1R1 | |
| SCHEMBL5889515 | 0.79 | KMT2A (0.41) | MAPTALDH1A1SMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL27949094 | 0.78 | TSHR (0.48) | ALDH1A1TAS1R3TAS1R1TSHRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504413-B2 | N-(4-(imidazo[1,2A]pyridin-YL)phenethyl)benzamide inhibitors of the mitotic kinesin CENP-E for treating certain cellular proliferation diseases | CYTOKINETICS, INC. (US) | 2009-03-17 | — | — | US | disclosed |