SCHEMBL78118

SCHEMBL78118

Cc1cn([C@H]2CC[C@@H](C)O2)c(=O)[nH]c1=O

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.53
DHFR P00374 1/20 0.50
ALB P02768 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
ADRA1A P35348 1/20 0.48
BLM P54132 1/20 0.48
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19242604 1.00 TK1 (0.53) TK1DHFRALBALDH1A1LMNA
Phosphoric Acid SCHEMBL3095605 0.93 TK1 (0.52) TK1DHFR
SCHEMBL9549703 0.91 TK1 (0.50) TK1DHFRALBALDH1A1LMNA
SCHEMBL9549708 0.90 TK1 (0.48) TK1DHFRALBALDH1A1LMNA
Pyrophosphoric Acid SCHEMBL1269545 0.89 POLB (0.54) TK1DHFRPOLB
SCHEMBL9549653 0.89 TK1 (0.50) TK1DHFRALBALDH1A1LMNA
Triphosphate SCHEMBL81707 0.87 POLB (0.55) TK1DHFRPOLB
SCHEMBL3154831 0.86 POLB (0.57) TK1DHFRPOLB
SCHEMBL9549656 0.86 TK1 (0.50) TK1DHFRALBALDH1A1LMNA
SCHEMBL5318941 0.85 TK1 (0.48) TK1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071254-A1 POLYMERASE MEDIATED END MODIFICATION OF ABSEQ BECTON DICKINSON CO (US) 2026-03-12 US claimed
EP-4612322-A1 POLYMERASE MEDIATED END MODIFICATION OF ABSEQ Becton, Dickinson and Company (US) 2025-09-10 EP claimed
CN-120019159-A Polymerase mediated ABSEQ terminal modification 贝克顿迪金森公司 2025-05-16 CN claimed
CN-119948173-A Modified molecular beacons for improved detection specificity 贝克顿迪金森公司 2025-05-06 CN claimed
WO-2025043082-A2 COMPOSITIONS AND METHODS TO IMPROVE RNA PROPERTIES USING BASE, PHOSPHODIESTER LINKAGE, SUGAR BACKBONE, AND CAP MODIFICATIONS THE BROAD INSTITUTE, INC. (US) 2025-02-27 WO claimed
US-12173365-B2 Sequencing using non-natural nucleotides ULTIMA GENOMICS, INC. (US) 2024-12-24 US claimed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 CN claimed
EP-4466074-A1 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF The Broad Institute Inc. (US) 2024-11-27 EP claimed
CN-118914407-A Method for detecting dinucleotide in drinking water by solid phase extraction-nitrogen blowing concentration-liquid chromatography tandem mass spectrometry 浙江大学 2024-11-08 CN claimed
WO-2024192269-A2 ENZYMATIC METHODS AND COMPOSITIONS FOR POLYMERIZATION OF PHOSPHORAMIDATE AND THIOPHOSPHORAMIDATE-LINKED DNA THE GENERAL HOSPITAL CORPORATION (US) 2024-09-19 WO claimed
WO-1991005060-A2 SPECTRALLY RESOLVABLE RHODAMINE DYES FOR NUCLEIC ACID SEQUENCE DETERMINATION APPLIED BIOSYSTEMS, INC. (US) 1991-04-18 WO claimed
EP-0416011-A1 CHEMOTHERAPEUTIC COMPOSITION FOR AIDS THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1991-03-13 EP claimed
EP-0378621-A1 DIAGNOSTICS AND THERAPY FOR RHEUMATOID ARTHRITIS GAY, Steffen (US) 1990-07-25 EP claimed
EP-0362359-A1 ANTIVIRAL COMPOSITION CONTAINING AROMATIC POLYCYCLIC DIONES AND NUCLEOSIDE ANALOGS AND METHOD FOR TREATING RETROVIRUS INFECTIONS NEW YORK UNIVERSITY (US) 1990-04-11 EP claimed
EP-0350287-A2 Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use NeXstar Pharmaceuticals, Inc. (US) 1990-01-10 EP claimed
WO-1989011274-A1 CHEMOTHERAPEUTIC COMPOSITION FOR AIDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-11-30 WO claimed
WO-1989011285-A1 DIAGNOSTICS AND THERAPY FOR RHEUMATOID ARTHRITIS GAY STEFFEN (US) 1989-11-30 WO claimed
WO-1989009056-A1 ANTIVIRAL COMPOSITION CONTAINING AROMATIC POLYCYCLIC DIONES AND NUCLEOSIDE ANALOGS AND METHOD FOR TREATING RETROVIRUS INFECTIONS NEW YORK UNIVERSITY (US) 1989-10-05 WO claimed
WO-1989009055-A1 ANTIVIRAL COMPOSITION CONTAINING AROMATIC POLYCYCLIC DIONES AND NUCLEOSIDE ANALOGS AND METHOD FOR TREATING RETROVIRUS INFECTIONS NEW YORK UNIVERSITY (US) 1989-10-05 WO claimed
EP-0272007-A2 5- and 6- Succinimidyl - carboxylate isomers of rhodamine dyes APPLIED BIOSYSTEMS, INC. (US) 1988-06-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071254-A1 POLYMERASE MEDIATED END MODIFICATION OF ABSEQ RNGTT, CTDSP1, DUT TK1 212/4885DHFR 1251/4885ALB 1768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.