Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349712 | 0.86 | KMT2A (0.60) | HPGDMEN1CASP3KMT2ASENP8 | |
| SCHEMBL13954049 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1MEN1CASP3KMT2ASENP8 | |
| SCHEMBL13933871 | 0.82 | ALDH1A1 (0.42) | ALDH1A1NPSR1HPGDHTTMEN1 | |
| SCHEMBL14349899 | 0.81 | KDM4E (0.53) | ALDH1A1NPSR1HPGDHTTCASP3 | |
| SCHEMBL13933869 | 0.79 | ALDH1A1 (0.57) | ALDH1A1NPSR1HPGDHTTMEN1 | |
| SCHEMBL6784915 | 0.75 | KMT2A (0.57) | ALDH1A1MEN1CASP3KMT2ASENP8 | |
| SCHEMBL7315505 | 0.73 | ALDH1A1 (0.61) | ALDH1A1NPSR1HPGDHTTKMT2A | |
| SCHEMBL6781577 | 0.73 | KMT2A (0.58) | HPGDMEN1CASP3KMT2ASENP8 | |
| SCHEMBL14349807 | 0.73 | ALDH1A1 (0.49) | ALDH1A1NPSR1HPGDHTTMEN1 | |
| SCHEMBL14340936 | 0.73 | ALDH1A1 (0.57) | ALDH1A1NPSR1HPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042926-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | MERCK SHARP & DOHME CORP. | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042926-A1 | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment | HCAR1, HCAR2, GPR119 | ALDH1A1 1145/4885NPSR1 43/4885HPGD 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.