Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PCNA | P12004 | 2/20 | 0.43 |
| ▸ | CHRND | Q07001 | 5/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16021246 | 0.94 | FOLH1 (0.49) | ALDH1A1FOLH1EGFRPOLB | |
| SCHEMBL16021241 | 0.92 | ALDH1A1 (0.45) | ALDH1A1NPSR1FOLH1PCNAEGFR | |
| SCHEMBL31072235 | 0.91 | ALDH1A1 (0.48) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL13123764 | 0.91 | ALDH1A1 (0.48) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL16021248 | 0.90 | FOLH1 (0.47) | ALDH1A1FOLH1PCNAEGFRPOLB | |
| SCHEMBL23864850 | 0.89 | ALDH1A1 (0.47) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL21466071 | 0.88 | ALDH1A1 (0.50) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL29352083 | 0.88 | ALDH1A1 (0.50) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL24091032 | 0.88 | ALDH1A1 (0.46) | ALDH1A1NPSR1BACE1MDM4MDM2 | |
| SCHEMBL21884113 | 0.86 | ALDH1A1 (0.46) | ALDH1A1NPSR1BACE1MDM4MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778761-B1 | INHERENTLY RADIOPAQUE BIORESORBABLE POLYMERS FOR MULTIPLE USES | REVA MEDICAL INC (US) | 2021-09-29 | — | — | EP | disclosed |
| US-7473417-B2 | Inherently radiopaque bioresorbable polymers for multiple uses | REVA MEDICAL, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-7473417-B2 | Inherently radiopaque bioresorbable polymers for multiple uses | REVA MEDICAL, INC. (US) | 2009-01-06 | — | — | US | disclosed |