SCHEMBL16021248

SCHEMBL16021248

CCOC(=O)C(Cc1ccc(O)c(I)c1)NC(=O)CCc1cc(I)c(O)c(I)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.47
ALDH1A1 P00352 4/20 0.45
POLB P06746 3/20 0.42
LCK P06239 1/20 0.41
PCNA P12004 3/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
ALB P02768 3/20 0.40
IL2 P60568 3/20 0.40
EGFR P00533 1/20 0.40
TP53 P04637 1/20 0.39
HDAC1 Q13547 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16021241 0.95 ALDH1A1 (0.45) FOLH1ALDH1A1POLBLCKPCNA
SCHEMBL16021246 0.95 FOLH1 (0.49) FOLH1ALDH1A1POLBLCKALB
SCHEMBL13938296 0.90 ALDH1A1 (0.46) FOLH1ALDH1A1POLBPCNAEGFR
SCHEMBL31072235 0.90 ALDH1A1 (0.48) ALDH1A1POLBPCNA
SCHEMBL13123764 0.90 ALDH1A1 (0.48) ALDH1A1POLBPCNA
SCHEMBL24091032 0.87 ALDH1A1 (0.46) ALDH1A1POLBPCNA
SCHEMBL13346556 0.87 FOLH1 (0.46) FOLH1POLBLCKPCNATHRA
SCHEMBL24091040 0.85 PCNA (0.54) ALDH1A1POLBPCNA
SCHEMBL14137770 0.83 FOLH1 (0.51) FOLH1ALDH1A1POLBLCKPCNA
SCHEMBL13346550 0.82 FOLH1 (0.47) FOLH1POLBLCKALBIL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9770465-B2 Inherently radiopaque polymeric products for embolotherapy RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-09-26 US disclosed
US-20140255335-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140255335-A1 INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY CD47, FGB, ELANE FOLH1 293/4885ALDH1A1 3266/4885POLB 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.