Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 5/20 | 0.70 |
| ▸ | GABBR1 | Q9UBS5 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18386267 | 1.00 | GABBR2 (0.70) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL2223571 | 0.88 | FNTA (0.54) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL11322774 | 0.83 | FFAR1 (0.54) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL2996427 | 0.83 | FFAR1 (0.61) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| SCHEMBL28801346 | 0.83 | GABBR2 (0.72) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| Phenibut SCHEMBL351501 | 0.82 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| Phenibut SCHEMBL9545047 | 0.82 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| Phenibut SCHEMBL340838 | 0.82 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| Phenibut SCHEMBL28119792 | 0.81 | GABBR2 (0.89) | GABBR2GABBR1LMNACYP2C9CYP3A4 | |
| Baclofen SCHEMBL5556250 | 0.81 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017795-A1 | INDAZOLE COMPOUNDS FOR TREATING INFLAMMATORY DISORDERS, DEMYELINATING DISORDERS AND CANCERS | XANTHUS PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |