Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 6/20 | 1.00 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenibut SCHEMBL351501 | 1.00 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| Phenibut SCHEMBL340838 | 1.00 | GABBR2 (1.00) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| Phenibut SCHEMBL22831453 | 0.98 | GABBR2 (0.96) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| Phenibut SCHEMBL3053795 | 0.98 | GABBR2 (0.96) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| Phenibut SCHEMBL27912811 | 0.96 | GABBR2 (0.92) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| Phenibut SCHEMBL28119792 | 0.94 | GABBR2 (0.89) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| SCHEMBL503819 | 0.87 | GABBR2 (0.76) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| SCHEMBL27691658 | 0.86 | GABBR2 (0.75) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL7092228 | 0.85 | GABBR2 (0.73) | GABBR2GABBR1LMNACYP2C9CYP2C19 | |
| SCHEMBL6734410 | 0.85 | GABBR2 (0.73) | GABBR2GABBR1LMNACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11465135-B2 | Bifunctional chiral organocatalytic compound having excellent enantioselectivity, preparation method therefor, and method for producing non-natural gamma-amino acid from nitro compound by using same | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2022-10-11 | — | — | US | disclosed |
| US-20200406243-A1 | BIFUNCTIONAL CHIRAL ORGANOCATALYTIC COMPOUND HAVING EXCELLENT ENANTIOSELECTIVITY, PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING NON-NATURAL GAMMA-AMINO ACID FROM NITRO COMPOUND BY USING SAME | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2020-12-31 | — | — | US | disclosed |
| US-8791295-B2 | Method of producing purified optically acitve 4-amino-3-(substituted phenyl)butanoic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-29 | — | — | US | disclosed |
| US-8293926-B2 | Method of producing optically active 4-amino-3-substituted phenylbutanoic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20110087049-A1 | METHOD OF PRODUCING PURIFIED OPTICALLY ACITVE 4-AMINO-3-(SUBSTITUTED PHENYL)BUTANOIC ACID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-04-14 | — | — | US | disclosed |
| US-20090137819-A1 | Method of Producing Optically Active 4-Amino-3-Substituted Phenylbutanoic Acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
| CN-101018770-A | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARM INC (US) | 2007-08-15 | — | — | CN | disclosed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465135-B2 | Bifunctional chiral organocatalytic compound having excellent enantioselectivity, preparation method therefor, and method for producing non-natural gamma-amino acid from nitro compound by using same | NOTUM, ALDH7A1, AADAT | GABBR2 709/4885GABBR1 581/4885LMNA 4555/4885 |
| US-20200406243-A1 | BIFUNCTIONAL CHIRAL ORGANOCATALYTIC COMPOUND HAVING EXCELLENT ENANTIOSELECTIVITY, PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING NON-NATURAL GAMMA-AMINO ACID FROM NITRO COMPOUND BY USING SAME | NOTUM, ALDH7A1, AADAT | GABBR2 709/4885GABBR1 581/4885LMNA 4555/4885 |
| US-20090137819-A1 | Method of Producing Optically Active 4-Amino-3-Substituted Phenylbutanoic Acid | ALAD, ATP6V1B1, DAO | GABBR2 36/4885GABBR1 77/4885LMNA 2454/4885 |
| US-20110087049-A1 | METHOD OF PRODUCING PURIFIED OPTICALLY ACITVE 4-AMINO-3-(SUBSTITUTED PHENYL)BUTANOIC ACID COMPOUND | ALAD, OR10J3, ACMSD | GABBR2 44/4885GABBR1 41/4885LMNA 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.