SCHEMBL2223571

SCHEMBL2223571

Cc1ccc(C(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.54
FNTB P49356 2/20 0.54
FFAR1 O14842 3/20 0.53
GABBR2 O75899 4/20 0.52
GABBR1 Q9UBS5 4/20 0.52
LMNA P02545 2/20 0.52
CYP2C9 P11712 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP3A4 P08684 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
NFKB1 P19838 1/20 0.52
DRD3 P35462 1/20 0.52
BLM P54132 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
MEN1 O00255 1/20 0.52
THRB P10828 1/20 0.52
TSHR P16473 1/20 0.52
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2996427 0.94 FFAR1 (0.61) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL11322774 0.90 FFAR1 (0.54) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL2471169 0.89 FNTA (0.50) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL16249736 0.89 GABBR2 (0.61) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL18386267 0.88 GABBR2 (0.70) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL13940816 0.88 GABBR2 (0.70) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL11333086 0.87 FNTA (0.48) FNTAFNTBFFAR1GABBR2GABBR1
SCHEMBL10908214 0.84 FFAR1 (0.54) FFAR1KMT2ACYP2C19ACHESTAT3
SCHEMBL10253431 0.82 ATM (0.59) FNTAFNTBGABBR2GABBR1LMNA
SCHEMBL10252945 0.82 POLB (0.68) FNTAFNTBGABBR2GABBR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011085445-A1 FLOTATION REAGENTS TEEBEE HOLDINGS PTY LTD (AU) 2011-07-21 WO claimed
CN-117247317-A Based on CO 2 Method for synthesizing dicarboxylic acid/tricarboxylic acid compound 四川大学 2023-12-19 CN disclosed
EP-2059565-B1 MODIFIED COLORANTS WITH ALIPHATIC POLY-ACID GROUPS CABOT CORP (US) 2014-06-11 EP disclosed
US-8021471-B2 Modified colorants with aliphatic poly-acid groups CABOT CORPORATION (US) 2011-09-20 US disclosed
US-8021471-B2 Modified colorants with aliphatic poly-acid groups CABOT CORPORATION (US) 2011-09-20 US disclosed
WO-2011085445-A1 FLOTATION REAGENTS TEEBEE HOLDINGS PTY LTD (AU) 2011-07-21 WO disclosed
US-20080108826-A1 PREPARATION OF 4-ALKOXY-7-(TETRAHYDRO-PYRAN-4-YL)-BENZOTHIAZOL-2-YLAMINE DERIVATIVES HOFFMANN-LA ROCHE INC. 2008-05-08 US disclosed
US-20080083347-A1 Readily dispersible in liquid vehicles; stability; ink jet pigments; quality optical density on plain paper CABOT CORPORATION 2008-04-10 US disclosed
US-20080083347-A1 Readily dispersible in liquid vehicles; stability; ink jet pigments; quality optical density on plain paper CABOT CORPORATION 2008-04-10 US disclosed
WO-2008027405-A2 MODIFIED COLORANTS WITH ALIPHATIC POLY-ACID GROUPS CABOT CORPORATION (US) 2008-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080108826-A1 PREPARATION OF 4-ALKOXY-7-(TETRAHYDRO-PYRAN-4-YL)-BENZOTHIAZOL-2-YLAMINE DERIVATIVES HTR7, HTR4, BRD7 FNTA 2666/4885FNTB 1672/4885FFAR1 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.