Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.77 |
| ▸ | MEN1 | O00255 | 9/20 | 0.77 |
| ▸ | HTT | P42858 | 7/20 | 0.77 |
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944051 | 0.90 | LMNA (0.70) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL13100734 | 0.83 | MAPT (0.62) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL11913699 | 0.83 | MAPT (0.55) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL1659816 | 0.81 | MAPT (0.62) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL1659812 | 0.81 | MAPT (0.62) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL14438981 | 0.81 | MEN1 (0.78) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL18953055 | 0.81 | CTSL (0.79) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL18953047 | 0.81 | CTSL (0.79) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL13576487 | 0.81 | LMNA (0.81) | KMT2AMEN1HTTMAPTALDH1A1 | |
| SCHEMBL22337232 | 0.80 | KMT2A (0.83) | KMT2AMEN1HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023558-A1 | COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS | VM DISCOVERY INC. (US) | 2009-02-19 | — | — | WO | disclosed |