SCHEMBL13942897

SCHEMBL13942897

O=C(O)COCCOCCNC(=O)COCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ LMNA P02545 1/20 0.45
▸ EPHX2 P34913 1/20 0.43
▸ CASP3 P42574 2/20 0.41
▸ FABP7 O15540 1/20 0.40
▸ FABP5 Q01469 1/20 0.40
▸ PTGIR P43119 1/20 0.40
▸ TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376637 1.00 KMT2A (0.58) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL29687629 1.00 KMT2A (0.58) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL421253 0.98 KMT2A (0.58) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31309927 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557019 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL31749859 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL178765 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL259018 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL4557247 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3
SCHEMBL1593608 0.95 KMT2A (0.63) KMT2ASMN1; SMN2LMNAEPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559529-B2 NPY2 receptor agonists BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-02-24 — — US disclosed
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists BOEHRINGER INGELHEIM INT GMH (DE) 2025-12-18 — — US disclosed
US-20240360194-A1 New Peptides as Potent and Selective GIP Receptor Agonists SANOFI (FR) 2024-10-31 — — US disclosed
US-12054525-B2 NPY2 receptor agonists BOEHRINGER INGELHEIM INTERNATIOAL GMBH (DE) 2024-08-06 — — US disclosed
EP-4399224-A1 NEW PEPTIDES AS POTENT AND SELECTIVE GIP RECEPTOR AGONISTS Sanofi (FR) 2024-07-17 — — EP disclosed
US-20230340039-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2023-10-26 — — US disclosed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP disclosed
US-20230165932-A1 PCSK9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME LLC 2023-06-01 — — US disclosed
US-20230144324-A1 PCSK9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME LLC 2023-05-11 — — US disclosed
US-20230103631-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS SANOFI (FR) 2023-04-06 — — US disclosed
EP-4110800-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS SANOFI (FR) 2023-01-04 — — EP disclosed
EP-4058047-A1 NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2022-09-21 — — EP disclosed
EP-4021919-A1 PCSK9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2022-07-06 — — EP disclosed
WO-2021175974-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS SANOFI (FR) 2021-09-10 — — WO disclosed
WO-2021127460-A1 PCSK9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2021-06-24 — — WO disclosed
WO-2021094259-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-05-20 — — WO disclosed
US-20210139548-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-05-13 — — US disclosed
US-20210069288-A1 PCSK9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME LLC 2021-03-11 — — US disclosed
WO-2021041770-A1 PCSK9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2021-03-04 — — WO disclosed
WO-2009022013-A1 INSULIN ANALOGUES WITH AN ACYL AND AKLYLENE GLYCOL MOIETY NOVO NORDISK A/S (DK) 2009-02-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139548-A1 NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R KMT2A 991/4885SMN1; SMN2 1118/4885LMNA 2884/4885
US-12054525-B2 NPY2 receptor agonists NPY2R, NPY1R, NPY5R KMT2A 991/4885SMN1; SMN2 1118/4885LMNA 2884/4885
US-20210069288-A1 PCSK9 ANTAGONIST COMPOUNDS PCSK9, PCSK7, PCSK6 KMT2A 1433/4885SMN1; SMN2 3778/4885LMNA 385/4885
US-20230165932-A1 PCSK9 ANTAGONIST COMPOUNDS PCSK9, PCSK7, PCSK6 KMT2A 1433/4885SMN1; SMN2 3778/4885LMNA 385/4885
US-20240360194-A1 New Peptides as Potent and Selective GIP Receptor Agonists GIPR, GLP1R, GPR119 KMT2A 4159/4885SMN1; SMN2 3401/4885LMNA 4777/4885
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists GLP1R, GIPR, NPY1R KMT2A 2259/4885SMN1; SMN2 1188/4885LMNA 3861/4885
US-20230103631-A1 PEPTIDES AS SELECTIVE GIP RECEPTOR AGONISTS GIPR, GLP1R, GPR119 KMT2A 4035/4885SMN1; SMN2 3419/4885LMNA 4794/4885
US-20230144324-A1 PCSK9 ANTAGONIST COMPOUNDS PCSK9, PCSK7, PCSK6 KMT2A 1269/4885SMN1; SMN2 3368/4885LMNA 493/4885
US-20230340039-A1 NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R KMT2A 991/4885SMN1; SMN2 1118/4885LMNA 2884/4885
US-12559529-B2 NPY2 receptor agonists NPY2R, NPY5R, NPY1R KMT2A 679/4885SMN1; SMN2 1470/4885LMNA 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback