SCHEMBL139461

SCHEMBL139461

C[CH]c1ccc(Cl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23244712 0.92 CYP1A2 (0.48)
SCHEMBL7040563 0.85 MAOB (0.52)
SCHEMBL2187090 0.83 ALDH1A1 (0.38)
SCHEMBL11516994 0.77 HSD17B10 (0.48)
SCHEMBL1425165 0.77 AHR (0.54)
SCHEMBL432740 0.77 AHR (0.54)
SCHEMBL11438751 0.77 AHR (0.54)
SCHEMBL260347 0.73 AHR (0.74)
SCHEMBL20582895 0.73 AHR (0.74)
SCHEMBL9679426 0.73 AHR (0.74)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192657-A1 1,2,4-TRIAZOLINONE CB1 INHIBITORS GFB (ABC), LLC 2023-06-22 US claimed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US claimed
EP-4114838-A1 1,2,4-TRIAZOLINONE CB1 INHIBITORS Goldfinch Bio, Inc. (US) 2023-01-11 EP claimed
CN-110023309-B Indazole derivatives as glucagon receptor antagonists 詹森药业有限公司 2022-08-09 CN claimed
US-11274083-B2 Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents SYNGENTA CROP PROTECTION AG (CH) 2022-03-15 US claimed
EP-3728237-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP claimed
EP-3728235-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP claimed
CN-113929696-A Acylthiourea psoralen derivatives, and preparation method and application thereof 南开大学 2022-01-14 CN claimed
US-20210087151-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2021-03-25 US claimed
EP-3169674-B1 ARYL-TRIAZOLYL-PYRIDINES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2021-01-20 EP claimed
EP-0125092-A1 Bisbiguanide compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP claimed
EP-0125093-A1 Diaz(ep)ine bis(N-amidinoamidine) derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP claimed
EP-0125091-A2 4,4'-Alkylenedipiperidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-11-14 EP claimed
US-4472412-A Control of fungi using phenylpropylammonium salts BASF AKTIENGESELLSCHAFT (DE) 1984-09-18 US claimed
US-4380633-A Methine dyes from tetrahydroquinoline compounds containing N-thioether substituents EASTMAN KODAK COMPANY (US) 1983-04-19 US claimed
US-4254031-A Synthesis for the preparation of tetracyclic compounds AKZONA INCORPORATED (US) 1981-03-03 US claimed
US-4243405-A HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-01-06 US claimed
US-4166827-A DENTAL PLAQUE COOPER LABORATORIES, INC. (US) 1979-09-04 US claimed
US-4110328-A Bis-carbamylguanidinoazaalkane antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-08-29 US claimed
US-3950387-A LIPID DISORDERS, ATHEROMATIC CONDITIONS RECHERCHES PHARMACEUTIQUES ET SCIENTIFIQUES (FR) 1976-04-13 US claimed