Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.61 |
| ▸ | HTR2C | P28335 | 14/20 | 0.57 |
| ▸ | CCR4 | P51679 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942959 | 0.88 | PIK3CA (0.64) | PIK3CAHTR2CCCR4 | |
| SCHEMBL13942985 | 0.88 | PIK3CA (0.62) | PIK3CAHTR2CCCR4 | |
| SCHEMBL13944733 | 0.86 | PIK3CA (0.83) | PIK3CAHTR2CCCR4 | |
| SCHEMBL13942984 | 0.83 | HTR2C (0.82) | PIK3CAHTR2CCCR4 | |
| SCHEMBL13944754 | 0.81 | HTR2C (0.53) | PIK3CAHTR2CCCR4 | |
| SCHEMBL13942986 | 0.81 | CTNNB1 (0.48) | PIK3CAHTR2CCCR4 | |
| SCHEMBL13947204 | 0.80 | HTR2C (0.58) | PIK3CAHTR2CCCR4 | |
| SCHEMBL2857218 | 0.77 | PIK3CA (0.74) | PIK3CAHTR2C | |
| SCHEMBL13944184 | 0.76 | PDE2A (0.59) | HTR2CCCR4 | |
| SCHEMBL13944361 | 0.76 | PIK3CA (1.00) | PIK3CAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |