Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.48 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 5/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | BCDIN3D | Q7Z5W3 | 6/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944754 | 0.90 | HTR2C (0.53) | CTNNB1TCF7L2HTR2CPIK3CABCDIN3D | |
| SCHEMBL13947574 | 0.90 | PDE2A (0.55) | HTR2CPDE2APIK3CABCDIN3D | |
| SCHEMBL13943714 | 0.85 | HTR2C (0.58) | HTR2CPDE2APIK3CABCDIN3D | |
| SCHEMBL13942959 | 0.85 | PIK3CA (0.64) | HTR2CPIK3CACCR4 | |
| SCHEMBL13944184 | 0.85 | PDE2A (0.59) | CTNNB1TCF7L2HTR2CPDE2ABCDIN3D | |
| SCHEMBL13947356 | 0.83 | PIK3CA (0.57) | HTR2CPDE2APIK3CABCDIN3D | |
| SCHEMBL13946788 | 0.81 | PIK3CA (0.61) | HTR2CPIK3CACCR4 | |
| SCHEMBL13943277 | 0.81 | PDE2A (0.70) | HTR2CPDE2APIK3CABCDIN3D | |
| SCHEMBL13947559 | 0.80 | NR3C1 (0.44) | CTNNB1TCF7L2HTR2CPDE2APIK3CA | |
| SCHEMBL13944174 | 0.80 | PDE2A (0.54) | HTR2CPDE2APIK3CABCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023978-A1 | PYRAZOLO [3,4 -D] PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF PROTEIN KINASE | ONCALIS AG (CH) | 2009-02-26 | — | — | WO | disclosed |