Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063 | 0.89 | CCR2 (0.50) | LMNAALDH1A1FFAR4HTTSMN1; SMN2 | |
| SCHEMBL13077435 | 0.89 | ALDH1A1 (0.52) | LMNAALDH1A1MRGPRX1FFAR4HTT | |
| SCHEMBL28093 | 0.78 | CCR2 (0.52) | LMNAALDH1A1FFAR4HTTSMN1; SMN2 | |
| SCHEMBL13586893 | 0.77 | ALDH1A1 (0.57) | LMNAALDH1A1FFAR4HTTSMN1; SMN2 | |
| SCHEMBL12051105 | 0.72 | CCR9 (0.66) | LMNAFFAR4HTTMAPTKMT2A | |
| SCHEMBL13484278 | 0.72 | FFAR4 (0.55) | ALDH1A1FFAR4HTTSMN1; SMN2POLB | |
| SCHEMBL14458036 | 0.71 | NAMPT (0.49) | LMNAALDH1A1NAMPTCCR2POLB | |
| SCHEMBL344756 | 0.71 | CCR9 (0.78) | LMNAHTT | |
| SCHEMBL13077398 | 0.70 | FFAR4 (0.53) | LMNAALDH1A1FFAR4HTTSMN1; SMN2 | |
| SCHEMBL17737455 | 0.70 | IDO1 (0.55) | LMNAALDH1A1FFAR4HTTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054495-A1 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054495-A1 | CCR9 inhibitors and methods of use thereof | CCR9, CCR1, CCR4 | LMNA 3548/4885ALDH1A1 2607/4885MRGPRX1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.