Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.49 |
| ▸ | CCR9 | P51686 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063 | 0.80 | CCR2 (0.50) | NAMPTCCR9ALDH1A1LMNACCR2 | |
| SCHEMBL344756 | 0.80 | CCR9 (0.78) | CCR9LMNA | |
| SCHEMBL13040759 | 0.74 | CCR9 (0.51) | CCR9ALDH1A1LMNATP53POLB | |
| SCHEMBL27433 | 0.73 | CCR9 (0.74) | CCR9LMNATP53 | |
| SCHEMBL28412 | 0.73 | CCR9 (0.69) | CCR9LMNATP53 | |
| SCHEMBL1436901 | 0.72 | CCR2 (0.47) | CCR9ALDH1A1LMNATP53CCR2 | |
| SCHEMBL27420 | 0.72 | CCR9 (0.68) | CCR9LMNATP53 | |
| SCHEMBL17737480 | 0.72 | FFAR4 (0.46) | CCR9ALDH1A1LMNATP53CCR2 | |
| SCHEMBL13950285 | 0.71 | LMNA (0.51) | NAMPTALDH1A1LMNACCR2POLB | |
| SCHEMBL2616503 | 0.71 | CCR9 (0.50) | CCR9ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238717-B2 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238717-B2 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-07-03 | — | — | US | disclosed |