Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093 | 0.90 | CCR2 (0.52) | ALDH1A1LMNACCR2FFAR4ADRB2 | |
| SCHEMBL13950285 | 0.89 | LMNA (0.51) | ALDH1A1LMNAMRGPRX1CCR2FFAR4 | |
| SCHEMBL28063 | 0.80 | CCR2 (0.50) | ALDH1A1LMNACCR2FFAR4TRIM24 | |
| SCHEMBL13586893 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNACCR2FFAR4POLB | |
| SCHEMBL4911520 | 0.71 | CCR2 (0.76) | ALDH1A1CCR2POLBKMT2AL3MBTL1 | |
| SCHEMBL12584919 | 0.69 | CCR2 (0.54) | ALDH1A1LMNACCR2FFAR4ADRB2 | |
| SCHEMBL5018912 | 0.68 | TDP1 (0.56) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12359492 | 0.68 | CCR9 (0.84) | LMNAMAPTHTTKMT2A | |
| SCHEMBL7571609 | 0.67 | MAPT (0.54) | ALDH1A1LMNACCR2TRIM24BRD1 | |
| SCHEMBL13950287 | 0.67 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280074-A1 | CCR9 INHIBITORS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20090054495-A1 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280074-A1 | CCR9 INHIBITORS AND METHODS OF USE THEREOF | CCR9, CCR1, CCR4 | ALDH1A1 2607/4885LMNA 3548/4885MRGPRX1 72/4885 |
| US-20090054495-A1 | CCR9 inhibitors and methods of use thereof | CCR9, CCR1, CCR4 | ALDH1A1 2607/4885LMNA 3548/4885MRGPRX1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.