Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 4/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130510 | 0.77 | NFE2L2 (0.50) | CYP1A2RELANFE2L2CYP19A1 | |
| SCHEMBL13241220 | 0.75 | CHRM2 (0.35) | FBP1 | |
| SCHEMBL13779257 | 0.74 | RAF1 (0.41) | CYP1A2RELAFBP1NFE2L2CCNB2 | |
| SCHEMBL13930343 | 0.73 | RELA (0.59) | CYP1A2TDP1RELAFBP1NFE2L2 | |
| SCHEMBL28665112 | 0.73 | RELA (0.59) | CYP1A2TDP1RELAFBP1NFE2L2 | |
| SCHEMBL29066455 | 0.73 | LCK (0.61) | FBP1ABL1BCRCCNB2CDK1 | |
| SCHEMBL878514 | 0.72 | ALDH1A1 (0.50) | CHRM5CYP1A2CYP3A4 | |
| SCHEMBL1109098 | 0.72 | SLC9A1 (0.37) | CHRM5CYP1A2CYP3A4RECQLTDP1 | |
| SCHEMBL8056512 | 0.72 | NFE2L2 (0.65) | CHRM5CYP1A2CYP3A4RELAFBP1 | |
| SCHEMBL8056513 | 0.72 | NFE2L2 (0.65) | CHRM5CYP1A2CYP3A4RELAFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090043111-A1 | Novel process for ropinirole preparation | LIU MEIZHENG | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043111-A1 | Novel process for ropinirole preparation | PAH, DRD4, DBH | CHRM5 2886/4885CYP1A2 78/4885CYP3A4 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.