Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10760842 | 0.97 | POLB (0.78) | POLBABCB1LMNAMAPK1KDM4E | |
| SCHEMBL6931910 | 0.85 | MAPK1 (0.69) | POLBLMNAMAPK1KDM4ETDP1 | |
| SCHEMBL258823 | 0.82 | HIF1A (0.75) | POLBABCB1LMNACYP2D6ADRB2 | |
| SCHEMBL31414644 | 0.81 | ALDH1A1 (0.67) | POLBLMNAMAPK1KDM4ETDP1 | |
| SCHEMBL6027881 | 0.81 | POLB (0.81) | POLBLMNAMAPK1KDM4ECYP2D6 | |
| SCHEMBL13246331 | 0.81 | POLB (0.58) | POLBLMNAMAPK1KDM4ETDP1 | |
| SCHEMBL13866493 | 0.81 | POLB (0.81) | POLBLMNAMAPK1KDM4ECYP2D6 | |
| SCHEMBL31414645 | 0.81 | ALDH1A1 (0.67) | POLBLMNAMAPK1KDM4ETDP1 | |
| SCHEMBL759782 | 0.81 | ALDH1A1 (0.67) | POLBLMNAMAPK1KDM4ETDP1 | |
| SCHEMBL11882594 | 0.81 | MAPK1 (0.63) | POLBLMNAMAPK1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018588-A2 | POLYURETHANE COATING | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-02-05 | — | — | WO | disclosed |