Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882594 | 0.91 | MAPK1 (0.63) | MAPK1KDM4ETDP1POLBMEN1 | |
| SCHEMBL13299368 | 0.87 | ABCB1 (0.67) | MAPK1KDM4ETDP1POLBMEN1 | |
| SCHEMBL11882590 | 0.86 | MAPK1 (0.53) | MAPK1KDM4ETDP1POLBMEN1 | |
| SCHEMBL10760842 | 0.85 | POLB (0.78) | MAPK1KDM4ETDP1POLBALDH1A1 | |
| SCHEMBL13952042 | 0.85 | POLB (0.78) | MAPK1KDM4ETDP1POLBALDH1A1 | |
| SCHEMBL9787234 | 0.84 | MAPK1 (0.52) | MAPK1KDM4ETDP1POLBMEN1 | |
| SCHEMBL9787231 | 0.84 | MAPK1 (0.52) | MAPK1KDM4ETDP1POLBMEN1 | |
| SCHEMBL759782 | 0.84 | ALDH1A1 (0.67) | MAPK1KDM4ETDP1POLBNPSR1 | |
| SCHEMBL15296872 | 0.82 | POLB (0.53) | MAPK1KDM4ETDP1POLBMEN1 | |
| SCHEMBL13299376 | 0.82 | ABCB1 (0.61) | MAPK1KDM4ETDP1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | disclosed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | disclosed |
| EP-0658583-B1 | Epoxy resin-hardener system having elastic properties | SOLUTIA GERMANY GMBH & CO KG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-0658584-B1 | Epoxy resin-hardener system having elastic properties | SOLUTIA GERMANY GMBH & CO KG (DE) | 2002-05-22 | — | — | EP | disclosed |
| EP-0617069-B1 | Curable, powdery mixtures | HOECHST AG (DE) | 2000-11-02 | — | — | EP | disclosed |
| EP-0387692-B1 | Curable powdry mixtures | HOECHST AG (DE) | 1997-07-16 | — | — | EP | disclosed |
| US-5585446-A | EPOXY RESIN ADHESIVE COMPOSITION | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5567782-A | ELASTIC ADHESIVE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-22 | — | — | US | disclosed |
| EP-0703258-A2 | Curable, powdery mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-27 | — | — | EP | disclosed |
| US-5459208-A | Elasticity at low temperatures; automobile structural adhesive | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-17 | — | — | US | disclosed |
| EP-0675185-A2 | Elastic amine-modified epoxy resin composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
| EP-0658583-A2 | Epoxy resin-hardener system having elastic properties | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658584-A2 | Epoxy resin-hardener system having elastic properties | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-21 | — | — | EP | disclosed |
| EP-0617069-A2 | Curable, powdery mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-28 | — | — | EP | disclosed |
| US-4997907-A | Polyester, epoxy compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0387692-A2 | Curable powdry mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | MAPK1 3886/4885KDM4E 3464/4885TDP1 760/4885 |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2C, HTR2A, HTR3A | MAPK1 3827/4885KDM4E 2088/4885TDP1 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.