SCHEMBL1395217

SCHEMBL1395217

CCCc1ccc([Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.45
LIPG Q9Y5X9 2/20 0.45
CA2 P00918 1/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
MGLL Q99685 1/20 0.39
PLK1 P53350 1/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 2/20 0.39
CTDSP1 Q9GZU7 2/20 0.39
NISCH Q9Y2I1 1/20 0.39
HTR1D P28221 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
THRB P10828 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19822667 0.94 NPC1 (0.46) LPLLIPGCA2RAB9ANPC1
SCHEMBL3186842 0.86 CA2 (0.48) LPLLIPGCA2PLK1ALDH1A1
SCHEMBL5481942 0.85 ALDH1A1 (0.53) LPLLIPGCA2RAB9AMAPT
SCHEMBL8377567 0.84 LPL (0.43) LPLLIPGCA2RAB9ANPC1
SCHEMBL19822664 0.83 HSD17B10 (0.57) LPLLIPGRAB9AMAPTMGLL
SCHEMBL5490185 0.83 HSD17B10 (0.57) LPLLIPGRAB9AMAPTMGLL
SCHEMBL1395155 0.82 LPL (0.42) LPLLIPGCA2RAB9ANPC1
SCHEMBL19822666 0.81 RARB (0.51) CA2RAB9ANPC1MAPTALDH1A1
SCHEMBL3481645 0.80 TP53 (0.43) LPLLIPGCA2RAB9ANPC1
SCHEMBL19822668 0.80 RARB (0.53) LPLLIPGRAB9AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10254668-B2 Toner for electrophotography, developer for electrophotography, image forming apparatus, and process cartridge RICOH COMPANY, LTD (JP) 2019-04-09 US disclosed
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME UBE INDUSTRIES, LTD. (JP) 2018-08-02 US disclosed
US-20180067409-A1 TONER FOR ELECTROPHOTOGRAPHY, DEVELOPER FOR ELECTROPHOTOGRAPHY, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2018-03-08 US disclosed
EP-3181569-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK CONTAINING SAME, AND ORGANIC ELECTRONIC DEVICE USING SAME UBE Industries, Ltd. (JP) 2017-06-21 EP disclosed
EP-1617294-B1 Toner for developing electrostatic image, method for producing the same, developer, image forming apparatus, process cartridge, and image forming method RICOH CO LTD (JP) 2015-12-23 EP disclosed
EP-2068199-B1 Image forming apparatus, toner, and process cartridge RICOH CO LTD (JP) 2015-08-12 EP disclosed
US-8697326-B2 Method of manufacturing a carrier, a carrier, a development agent, and a process cartridge RICOH COMPANY, LTD. (JP) 2014-04-15 US disclosed
US-8377618-B2 Image forming method, image forming apparatus, and toner RICOH COMPANY LIMITED (JP) 2013-02-19 US disclosed
EP-1624345-B1 Full color toner, image forming method, fixing device, developer, process cartridge, and image forming apparatus RICOH CO LTD (JP) 2013-02-13 EP disclosed
US-8247150-B2 Carrier for developing electrostatic latent image, two-component developer, supplemental developer, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2012-08-21 US disclosed
US-6258502-B1 MAGNETIC CARRIER AND TONER RICOH COMPANY, LTD. (JP) 2001-07-10 US disclosed
US-6200719-B1 A TONER FOR DEVELOPING LATENT ELECTROSTATIC IMAGES TO TONER IMAGES, WHICH HAS EXCELLENT OFFSET-RESISTANCE, FLUIDITY AND DURABILITY AND COMPRISES PARTICLES CONTAINING, COLORING AGENT, RELEASE AGENT AND BINDER RESIN RICOH COMPANY, LTD. (JP) 2001-03-13 US disclosed
US-6183926-B1 FLUIDITY; IMAGE FIXING; MINIMIZATION OF CONTAMINATION OF FILMING PHENOMENON OF PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2001-02-06 US disclosed
US-6180298-B1 COLOR TONERS FOR DEVELOPING LATENT ELECTROSTATIC IMAGES TO FORM MULTI-COLOR IMAGES RICOH COMPANY, LTD. (JP) 2001-01-30 US disclosed
EP-1055970-A1 Two-component developer, two-component developer holding container, and electrophotographic image formation apparatus equipped with the container Ricoh Company, Ltd. (JP) 2000-11-29 EP disclosed
EP-1043630-A2 Toner, method of producting the toner, image formation method using the toner, and toner container Ricoh Company, Ltd. (JP) 2000-10-11 EP disclosed
US-6074795-A BINDER RESINS, COLORS AND RELEASING AGENTS WITH ABSORPTION RICOH COMPANY, LTD. (JP) 2000-06-13 US disclosed
EP-0997786-A1 Toner and two-component developer for electrophotographic process and image formation method and image formation apparatus using the toner Ricoh Company, Ltd. (JP) 2000-05-03 EP disclosed
US-6010813-A MIXTURE OF COLORED PARTICLES, STYRENE-ACRYL COPOLYMER BINDER AND TITANIUM OXIDE KONICA CORPORATION (JP) 2000-01-04 US disclosed
US-4585723-A SILICON DIOXIDE PARTICLES MADE HYDROPHOBIC KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME IKZF3, HELZ, TEC LPL 4664/4885LIPG 4397/4885CA2 2907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.