Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078047 | 0.82 | KDM4E (0.46) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4433337 | 0.78 | NPC1 (0.38) | MAPTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11933957 | 0.77 | CYP1B1 (0.44) | APOBEC3AAPOBEC3GMAPTSMN1; SMN2CA12 | |
| SCHEMBL30892213 | 0.73 | CA12 (0.56) | APOBEC3GMAPTSMN1; SMN2CA12CA1 | |
| SCHEMBL12463621 | 0.73 | CA12 (0.56) | APOBEC3GMAPTSMN1; SMN2CA12CA1 | |
| SCHEMBL12878065 | 0.73 | MPI (0.46) | APOBEC3AAPOBEC3GMAPTSMN1; SMN2CA12 | |
| SCHEMBL29007575 | 0.73 | CA12 (0.40) | MAPTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL987451 | 0.73 | GAA (0.41) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL3434561 | 0.73 | CA12 (0.56) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL13952761 | 0.72 | TUBB4A (0.39) | MAPTSMN1; SMN2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042820-A1 | Tubulin Binding Anti Cancer Agents And Prodrugs Thereof | THRESHOLD PHARMACEUTICALS, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042820-A1 | Tubulin Binding Anti Cancer Agents And Prodrugs Thereof | TUBB1, TUBB, TUBB6 | APOBEC3A 4605/4885APOBEC3G 4673/4885MAPT 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.