Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404555 | 0.93 | CCR5 (0.44) | MEN1KMT2AALDH1A1RAB9ASIGMAR1 | |
| SCHEMBL14297341 | 0.84 | NPC1 (0.55) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17896798 | 0.80 | NPC1 (0.56) | MEN1KMT2ANPC1MAP4K4SIGMAR1 | |
| SCHEMBL2575803 | 0.79 | MEN1 (0.51) | MEN1KMT2AMAP4K4SIGMAR1CCR5 | |
| SCHEMBL4283829 | 0.79 | CCR5 (0.62) | KMT2AALDH1A1SIGMAR1CCR5 | |
| SCHEMBL19444606 | 0.78 | CCR5 (0.64) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11626650 | 0.78 | MAP4K4 (0.57) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL2406042 | 0.78 | CCR5 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL11394433 | 0.77 | SIGMAR1 (0.64) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2407533 | 0.75 | KCNH2 (0.49) | MEN1KMT2ARAB9ANPC1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485707-B1 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | CAPROTEC BIOANALYTICS GMBH (DE) | 2009-01-14 | — | — | EP | disclosed |