Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 9/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434079 | 0.92 | CCR5 (0.63) | CCR5SIGMAR1KCNH2 | |
| SCHEMBL14297341 | 0.86 | NPC1 (0.55) | CCR5SIGMAR1KCNH2ALDH1A1KMT2A | |
| SCHEMBL2575803 | 0.84 | MEN1 (0.51) | CCR5SIGMAR1KCNH2KMT2A | |
| SCHEMBL29116794 | 0.83 | L3MBTL1 (0.57) | CCR5SIGMAR1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL12359048 | 0.83 | CCR5 (0.69) | CCR5SIGMAR1KCNH2KMT2A | |
| SCHEMBL19444606 | 0.83 | CCR5 (0.64) | CCR5ALDH1A1L3MBTL1KMT2AEPHX2 | |
| SCHEMBL11626650 | 0.83 | MAP4K4 (0.57) | CCR5SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL11394433 | 0.82 | SIGMAR1 (0.64) | CCR5SIGMAR1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL17896798 | 0.82 | NPC1 (0.56) | CCR5SIGMAR1KMT2A | |
| SCHEMBL4278254 | 0.82 | L3MBTL1 (0.60) | SIGMAR1ALDH1A1ATML3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | CCR5 4090/4885SIGMAR1 1349/4885KCNH2 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.