Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | CCR5 | P51681 | 16/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941872 | 0.85 | SIGMAR1 (0.60) | KCNA3CCR5LTA4H | |
| SCHEMBL13960303 | 0.85 | KCNA3 (0.66) | KCNA3CCR5OPRM1OPRL1 | |
| SCHEMBL3940343 | 0.83 | KCNA3 (0.62) | KCNA3CCR5LTA4HOPRM1OPRL1 | |
| SCHEMBL13961156 | 0.82 | KCNA3 (0.58) | KCNA3CCR5OPRM1OPRL1 | |
| SCHEMBL2980930 | 0.79 | DRD2 (0.67) | LTA4H | |
| SCHEMBL3636812 | 0.79 | LTA4H (0.50) | LTA4HOPRM1 | |
| SCHEMBL3934500 | 0.78 | KCNA3 (0.59) | KCNA3CCR5OPRM1OPRL1 | |
| SCHEMBL13961369 | 0.77 | KCNA3 (0.62) | KCNA3CCR5OPRM1OPRL1 | |
| SCHEMBL844722 | 0.77 | LMNA (0.51) | LTA4HOPRL1 | |
| SCHEMBL6631280 | 0.77 | LTA4H (0.69) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010479-A2 | HETEROCYCLIC METHYLENE PIPERIDINE DERIVATIVES AND THEIR USE | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |