Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13961673 | 0.87 | DGAT1 (0.36) | TSHRMEN1KMT2ANPC1KLKB1 | |
| SCHEMBL12289528 | 0.86 | DGAT1 (0.34) | TSHRMEN1KMT2ANPC1USP2 | |
| SCHEMBL13961680 | 0.79 | — | — | |
| SCHEMBL13961674 | 0.79 | DGAT1 (0.32) | — | |
| SCHEMBL2423365 | 0.73 | NPC1 (0.36) | TSHRMEN1KMT2ANPC1 | |
| SCHEMBL22717628 | 0.72 | ALDH1A1 (0.38) | TSHRKMT2ANPC1USP2 | |
| SCHEMBL14697499 | 0.72 | NR3C1 (0.45) | TSHRMEN1KMT2A | |
| SCHEMBL13961678 | 0.72 | — | — | |
| SCHEMBL29482218 | 0.70 | RORC (0.40) | MEN1KMT2ANPC1 | |
| SCHEMBL17758611 | 0.70 | RORC (0.40) | MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009411-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |