Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812642 | 0.75 | EPHX1 (0.44) | TAAR1SLC6A2SLC6A3MEN1ALDH1A1 | |
| SCHEMBL13962958 | 0.75 | SLC1A3 (0.45) | TAAR1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL1696684 | 0.75 | SLC1A3 (0.45) | TAAR1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL19812643 | 0.73 | TAAR1 (0.47) | TAAR1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL27318990 | 0.69 | CYP1A2 (0.43) | SLC1A3SLC1A2SLC1A1MMEOPRM1 | |
| SCHEMBL15203049 | 0.68 | OPRM1 (0.40) | TAAR1SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL19812679 | 0.68 | TAAR1 (0.50) | TAAR1SLC1A1MDM2 | |
| SCHEMBL4668650 | 0.67 | DPP4 (0.46) | TAAR1SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL5321903 | 0.66 | — | — | |
| SCHEMBL9542385 | 0.66 | HTR2A (0.46) | TAAR1SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340026-A1 | COMPOUNDS | NEW PHARMA LICENCE HOLDINGS LTD (MT) | 2023-10-26 | — | — | US | disclosed |
| US-20180030092-A1 | COMPOUNDS | SPERO THERAPEUTICS, INC. | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340026-A1 | COMPOUNDS | BCAT1, BCAT2, CCNT1 | TAAR1 823/4885SLC1A3 565/4885SLC1A2 330/4885 |
| US-20180030092-A1 | COMPOUNDS | BCAT1, BCAT2, IL4I1 | TAAR1 886/4885SLC1A3 778/4885SLC1A2 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.