Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | BMPR1B | O00238 | 6/20 | 0.58 |
| ▸ | BMPR1A | P36894 | 6/20 | 0.58 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.58 |
| ▸ | ACVR1 | Q04771 | 6/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.53 |
| ▸ | USP7 | Q93009 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225948 | 0.85 | FYN (0.76) | FYNBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL18613238 | 0.83 | FYN (1.00) | FYNBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL4621190 | 0.82 | FYN (0.80) | FYNTGFBR1CHEK2 | |
| SCHEMBL13968129 | 0.80 | MAP4K4 (0.80) | FYNMAP4K4USP7CHEK2 | |
| SCHEMBL2224862 | 0.80 | CHEK2 (0.72) | FYNMAP4K4CHEK2 | |
| SCHEMBL4622807 | 0.80 | FYN (0.65) | FYNBMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL13968131 | 0.80 | MAP4K4 (0.54) | FYNMAP4K4MAPK14MINK1TNIK | |
| SCHEMBL13968133 | 0.78 | KCNH2 (0.75) | FYNMAP4K4PIK3C3 | |
| SCHEMBL5427032 | 0.78 | HDAC1 (0.62) | MAPK14MAPK13MAPK12MAPK11MEN1 | |
| SCHEMBL13968145 | 0.78 | BMPR1B (0.58) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024033-B2 | Anti-malarial agents | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2015-05-05 | — | — | US | disclosed |
| US-20120295905-A1 | NEW ANTI-MALARIAL AGENTS | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295905-A1 | NEW ANTI-MALARIAL AGENTS | QDPR, DHFR, ITPA | FYN 3839/4885BMPR1B 4852/4885BMPR1A 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.