SCHEMBL13969293

SCHEMBL13969293

c1ccc(N(c2ccc(N(c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)c3ccc(N(c4ccccc4)c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)cc2)c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.53
KDM4E B2RXH2 2/20 0.53
ATM Q13315 1/20 0.53
TSPO P30536 3/20 0.43
HDAC4 P56524 1/20 0.40
PTGER4 P35408 1/20 0.38
KMT2A Q03164 2/20 0.35
MAPK8 P45983 1/20 0.35
IL1R1 P14778 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.34
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
PTPN1 P18031 2/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13969301 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL13969326 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL13969286 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15306430 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15306455 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL13969333 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL13969285 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL10004856 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15306423 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL10310210 1.00 L3MBTL1 (0.53) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2022-05-31 US disclosed
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-06-13 US disclosed
US-10246441-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
US-20120292606-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-11-22 US disclosed
US-20120292606-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246441-B2 Aromatic amine derivative, and organic electroluminescent element MAOB, MAOA, NAT1 L3MBTL1 1183/4885KDM4E 433/4885ATM 696/4885
US-20190177306-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, LEF1, EFNA1 L3MBTL1 909/4885KDM4E 191/4885ATM 1091/4885
US-11345686-B2 Aromatic amine derivative, and organic electroluminescent element TYR, LEF1, EFNA1 L3MBTL1 909/4885KDM4E 191/4885ATM 1091/4885
US-20120292606-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT MAOB, MAOA, NAT1 L3MBTL1 1183/4885KDM4E 433/4885ATM 696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.