SCHEMBL139700

SCHEMBL139700

CCCCCCCCCCCCCCCCN1CCC(O)[C@@]1(CCCCCCCCCCCCCCCC)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 7/20 0.37
GNAO1 P09471 7/20 0.37
GNAI1 P63096 7/20 0.37
KCNH2 Q12809 1/20 0.36
BCHE P06276 3/20 0.36
CPB2 Q96IY4 1/20 0.35
GBA1 P04062 1/20 0.35
GUSB P08236 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28179503 0.77 GNAI3 (0.33) GNAI3GNAO1GNAI1BCHECPB2
SCHEMBL29028694 0.71 GBA1 (0.39) GNAI3GNAO1GNAI1BCHEGBA1
SCHEMBL8197075 0.69 KCNH2 (0.36) GNAI3GNAO1GNAI1KCNH2BCHE
SCHEMBL139702 0.69 GUSB (0.37) BCHECPB2GBA1GUSB
SCHEMBL5711571 0.68 GNAI3 (0.37) GNAI3GNAO1GNAI1KCNH2BCHE
SCHEMBL28110693 0.68 CPB2 (0.36) BCHECPB2
SCHEMBL18187498 0.66 GUSB (0.37) KCNH2BCHEGBA1GUSB
SCHEMBL10818617 0.64 L3MBTL1 (0.38) BCHE
SCHEMBL454182 0.64 S1PR1 (0.41) KCNH2BCHE
SCHEMBL6060680 0.64 AKT1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11083685-B2 Methods for treating scars and aging skin ALLERGAN, INC. (US) 2021-08-10 US disclosed
US-20160058816-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2016-03-03 US disclosed
US-20160058693-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN INC (US) 2016-03-03 US disclosed
US-9180158-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2015-11-10 US disclosed
US-9180157-B2 Methods for treating scars and aging skin ALLERGAN, INC. 2015-11-10 US disclosed
US-20130337088-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2013-12-19 US disclosed
US-8591961-B2 Aesthetic treatment of scars and aging skin ALLERGAN, INC. (US) 2013-11-26 US disclosed
US-20120058167-A1 METHODS FOR TREATING SCARS AND AGING SKIN ALLERGAN, INC. 2012-03-08 US disclosed
US-20120058076-A1 AESTHETIC TREATMENT OF SCARS AND AGING SKIN ALLERGAN, INC. 2012-03-08 US disclosed