Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349750 | 0.82 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL25348910 | 0.73 | — | — | |
| SCHEMBL139700 | 0.69 | GNAI3 (0.37) | KCNH2BCHEGNAI3GNAO1GNAI1 | |
| SCHEMBL14812011 | 0.69 | MAPK1 (0.33) | — | |
| SCHEMBL10818617 | 0.67 | L3MBTL1 (0.38) | BCHES1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15920931 | 0.67 | S1PR1 (0.38) | BCHES1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL11746132 | 0.66 | FAAH (0.35) | KCNH2BCHES1PR1S1PR3S1PR5 | |
| SCHEMBL18187498 | 0.66 | GUSB (0.37) | KCNH2BCHE | |
| SCHEMBL6237036 | 0.65 | S1PR1 (0.36) | KCNH2BCHES1PR1S1PR3S1PR5 | |
| SCHEMBL6229847 | 0.65 | S1PR1 (0.36) | KCNH2BCHES1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011650-A1 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | Amgen Inc., (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999014998-A2 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | AMGEN INC. (US) | 1999-04-01 | — | — | WO | disclosed |