Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420554 | 0.82 | — | — | |
| SCHEMBL14214169 | 0.75 | CAPN1 (0.37) | — | |
| SCHEMBL17021870 | 0.74 | SLC6A3 (0.37) | CYP1A2 | |
| SCHEMBL9640737 | 0.73 | CHRM3 (0.41) | — | |
| SCHEMBL118438 | 0.72 | NUDT1 (0.33) | — | |
| SCHEMBL17355090 | 0.72 | HPGD (0.30) | — | |
| Hydrochloric Acid SCHEMBL9642016 | 0.72 | CHRM3 (0.43) | — | |
| SCHEMBL13597364 | 0.71 | KDM1A (0.35) | CYP1A2 | |
| SCHEMBL2753905 | 0.71 | CYP2C19 (0.34) | CYP1A2 | |
| SCHEMBL12101116 | 0.71 | RIPK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011880-A2 | HETEROCYCLIC MODULATORS OF PKB | AMGEN INC. (US) | 2009-01-22 | — | — | WO | disclosed |