SCHEMBL1397158

SCHEMBL1397158

Oc1ccc(CCc2ccc(O)cc2O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TYR P14679 6/20 1.00
ALOX5 P09917 2/20 0.63
MEN1 O00255 2/20 0.63
MAPT P10636 2/20 0.63
KMT2A Q03164 2/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
ALOX15 P16050 1/20 0.63
TSHR P16473 1/20 0.63
HTT P42858 1/20 0.63
TDP1 Q9NUW8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4370686 0.90 TYR (0.81) TYRALOX5MEN1MAPTKMT2A
SCHEMBL24201406 0.89 TYR (0.78) TYRALOX5MEN1MAPTKMT2A
SCHEMBL1846350 0.89 TYR (0.78) TYRALOX5MEN1MAPTKMT2A
SCHEMBL8398793 0.87 TYR (0.81) TYRALOX5MEN1MAPTKMT2A
SCHEMBL8401997 0.87 TYR (0.81) TYRALOX5MEN1MAPTKMT2A
SCHEMBL8398763 0.87 TYR (0.81) TYRALOX5MEN1MAPTKMT2A
SCHEMBL950883 0.87 TYR (0.77) TYRALOX5MEN1MAPTKMT2A
SCHEMBL8401879 0.87 TYR (0.81) TYRALOX5MEN1MAPTKMT2A
SCHEMBL30045833 0.87 TYR (0.77) TYRALOX5MEN1MAPTKMT2A
SCHEMBL19433107 0.87 TYR (1.00) TYRALOX5MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4046619-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS Unigen, Inc. (US) 2022-08-24 EP claimed
US-8658838-B2 Series of skin whitening (lightening) compounds UNIGEN, INC. (US) 2014-02-25 US claimed
US-20130209383-A1 SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS UNIGEN, INC. (US) 2013-08-15 US claimed
EP-2323612-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS Unigen, Inc. (US) 2011-05-25 EP claimed
WO-2010011630-A1 SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS UNIGEN PHARMACEUTICALS, INC. (US) 2010-01-28 WO claimed
US-20100016347-A1 SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS UNIGEN PHARMACEUTICALS, INC. (US) 2010-01-21 US claimed
US-12227472-B2 Series of skin-whitening (lightening) compounds UNIGEN, INC. (US) 2025-02-18 US disclosed
US-20230399282-A1 Series of Skin-Whitening (Lightening) Compounds UNIGEN, INC. (US) 2023-12-14 US disclosed
US-20230399282-A1 Series of Skin-Whitening (Lightening) Compounds UNIGEN, INC. (US) 2023-12-14 US disclosed
US-20230399282-A1 Series of Skin-Whitening (Lightening) Compounds UNIGEN, INC. (US) 2023-12-14 US disclosed
US-11739040-B2 Series of skin-whitening (lightening) compounds UNIGEN, INC. (US) 2023-08-29 US disclosed
US-11739040-B2 Series of skin-whitening (lightening) compounds UNIGEN, INC. (US) 2023-08-29 US disclosed
US-11739040-B2 Series of skin-whitening (lightening) compounds UNIGEN, INC. (US) 2023-08-29 US disclosed
US-6512020-B1 Photosensitive acid-donors in chemically amplified resist formulations. activated by irradiation with actinic electromagnetic radiation and electron beams. CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-28 US disclosed
WO-2002098870-A1 SUBSTITUTED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-12 WO disclosed
WO-2002046507-A2 ONIUM SALTS AND THE USE THEROF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-06-13 WO disclosed
WO-2002025376-A2 OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-28 WO disclosed
US-20010036591-A1 Iodonium salts as latent acid donors IGM GROUP B.V. (NL) 2001-11-01 US disclosed
US-6306555-B1 RADIATION-SENSITIVE COMPOSITION COMPRISING CATIONICALLY OR ACID-CATALYTICALLY POLYMERISABLE OR CROSSLINKABLE COMPOUND OR COMPOUND THAT INCREASES ITS SOLUBILITY IN DEVELOPER UNDER ACTION OF ACID, AND AT LEAST ONE DIARYLIODONIUM SALT CIBA SPECIALTY CHEMICALS CORP. 2001-10-23 US disclosed
US-6261738-B1 LATENT CURING CATALYSTS FOR PHOTORESISTS SUCH AS 2,2,2-TRIFLUORO-1-PHENYL-ETHANONE OXIME-O-METHYL SULFONATE CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739040-B2 Series of skin-whitening (lightening) compounds TYR, TH, MAOB TYR 1/4885ALOX5 301/4885MEN1 2802/4885
US-20230399282-A1 Series of Skin-Whitening (Lightening) Compounds TYR, TH, MAOB TYR 1/4885ALOX5 301/4885MEN1 2802/4885
US-20130209383-A1 SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS TYR, MAOB, TH TYR 1/4885ALOX5 287/4885MEN1 2813/4885
US-20100016347-A1 SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS TYR, MAOB, TH TYR 1/4885ALOX5 287/4885MEN1 2813/4885
US-12227472-B2 Series of skin-whitening (lightening) compounds TYR, TH, MAOB TYR 1/4885ALOX5 301/4885MEN1 2802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.