SCHEMBL950883

SCHEMBL950883

OCCc1ccc(O)cc1O

nearest known ligand 0.77

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYR P14679 6/20 0.77
ALOX5 P09917 2/20 0.57
MEN1 O00255 1/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
MAPT P10636 1/20 0.57
ALOX15 P16050 1/20 0.57
TSHR P16473 1/20 0.57
HTT P42858 1/20 0.57
KMT2A Q03164 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
HTR2C P28335 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30045833 1.00 TYR (0.77) TYRALOX5MEN1TP53CYP3A4
SCHEMBL1397158 0.87 TYR (1.00) TYRALOX5MEN1TP53CYP3A4
SCHEMBL532243 0.86 TYR (0.71) TYRALOX5MEN1TP53CYP3A4
SCHEMBL4370686 0.83 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL27903131 0.83 TYR (0.52) TYRALOX5MEN1TP53CYP3A4
SCHEMBL1846489 0.83 TYR (0.70) TYRALOX5MEN1TP53CYP3A4
SCHEMBL2767004 0.82 CHRNA7 (0.53) TYRALOX5MEN1TP53CYP3A4
SCHEMBL8401997 0.81 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL8401879 0.81 TYR (0.81) TYRALOX5MEN1TP53CYP3A4
SCHEMBL1467498 0.81 TYR (0.50) TYRALOX5MEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US claimed
CN-101152132-A Hair dyeing cream FANG YE (CN) 2008-04-02 CN claimed
CN-114245792-A Compound, polymer, composition for film formation, method for pattern formation, method for forming insulating film, method for producing compound, and method for producing iodine-containing vinyl polymer and acetylated derivative thereof 三菱瓦斯化学株式会社 2022-03-25 CN disclosed
WO-2021029395-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMING METHOD, METHOD FOR FORMING INSULATING FILM, METHOD FOR PRODUCING COMPOUND, IODINE-CONTAINING VINYL POLYMER AND METHOD FOR PRODUCING ACETYLATED DERIVATIVE OF SAME 三菱瓦斯化学株式会社 2021-02-18 WO disclosed
WO-2021029395-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMING METHOD, METHOD FOR FORMING INSULATING FILM, METHOD FOR PRODUCING COMPOUND, IODINE-CONTAINING VINYL POLYMER AND METHOD FOR PRODUCING ACETYLATED DERIVATIVE OF SAME 三菱瓦斯化学株式会社 2021-02-18 WO disclosed
EP-3262015-B1 IONONE STABILISERS FOR NITROCELLULOSE-BASED PROPELLANTS P B CLERMONT (BE) 2019-03-27 EP disclosed
CN-108690505-A Paste compound for chemically mechanical polishing 三星电子株式会社 2018-10-23 CN disclosed
CN-106867411-A For the paste compound, its preparation method, polishing method, the method for manufacture semiconductor devices and the polissoir that chemically-mechanicapolish polish 三星电子株式会社 2017-06-20 CN disclosed
US-8178136-B2 Composition based on vegetal extracts of Ajuga reptans for preventing hair loss, stimulating the growth of hair, regulating the production of sebum GIULIANI S.P.A. (IT) 2012-05-15 US disclosed
EP-2355782-A2 A COMPLEX OF ACTIVE VEGETAL STEM CELLS AND A COSMETIC COMPOSITION LABO Cosprophar AG (CH) 2011-08-17 EP disclosed
US-20110020476-A1 Composition based on vegetal extracts of ajuga reptans for preventing hair loss, stimulating the growth of hair, regulating the production of sebum GIULIANI GIAMMARIA 2011-01-27 US disclosed
US-20080014322-A1 Olive Polyphenols Concentrate NATRACEUTICAL INDUSTRIAL S.L.U. (ES) 2008-01-17 US disclosed
US-20080003308-A1 Composition Based on Vegetal Extracts of Ajuga Reptans for Preventing Hair Loss, Stimulating the Growth of Hair, Regulating the Production of Sebum GIULIANI S.P.A. (IT) 2008-01-03 US disclosed
EP-1863430-A1 COMPOSITION BASED ON VEGETAL EXTRACTS OF AJUGA REPTANS FOR PREVENTING HAIR LOSS, STIMULATING THE GROWTH OF HAIR, REGULATING THE PRODUCTION OF SEBUM. GIULIANI S.p.A. (IT) 2007-12-12 EP disclosed
EP-1755412-A1 OLIVE POLYPHENOLS CONCENTRATE Natraceutical Industrial S.L.U. (ES) 2007-02-28 EP disclosed
WO-2006100101-A1 COMPOSITION BASED ON VEGETAL EXTRACTS OF AJUGA REPTANS FOR PREVENTING HAIR LOSS, STIMULATING THE GROWTH OF HAIR, REGULATING THE PRODUCTION OF SEBUM. GIULIANI S.P.A. (IT) 2006-09-28 WO disclosed
WO-2006005986-A1 OLIVE POLYPHENOLS CONCENTRATE NATRACEUTICAL INDUSTRIAL S.L.U. (ES) 2006-01-19 WO disclosed
US-6288096-B1 ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS ASTRAZENECA AB (SE) 2001-09-11 US disclosed
EP-0991632-A1 NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES Astra Aktiebolag (SE) 2000-04-12 EP disclosed
WO-1998057941-A1 NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES ASTRA AKTIEBOLAG (SE) 1998-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020476-A1 Composition based on vegetal extracts of ajuga reptans for preventing hair loss, stimulating the growth of hair, regulating the production of sebum SHBG, AR, NR5A1 TYR 467/4885ALOX5 615/4885MEN1 2864/4885
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 TYR 1/4885ALOX5 63/4885MEN1 4836/4885
US-20080003308-A1 Composition Based on Vegetal Extracts of Ajuga Reptans for Preventing Hair Loss, Stimulating the Growth of Hair, Regulating the Production of Sebum SHBG, AR, NR5A1 TYR 467/4885ALOX5 615/4885MEN1 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.