Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113598 | 0.82 | ALDH1A1 (0.42) | ATG4BCYP3A4MEN1KMT2AACKR3 | |
| SCHEMBL13370339 | 0.79 | CYP3A4 (0.54) | ATG4BCYP3A4MEN1KMT2AADORA2A | |
| SCHEMBL10113867 | 0.77 | ALDH1A1 (0.40) | ATG4BMEN1KMT2AACKR3ADORA2A | |
| SCHEMBL13035844 | 0.71 | L3MBTL1 (0.52) | ATG4BMEN1KMT2AADORA2AADORA1 | |
| SCHEMBL13972705 | 0.71 | MEN1 (0.69) | MEN1KMT2AMAPT | |
| SCHEMBL2937018 | 0.70 | CYP1A2 (0.54) | ATG4BADORA2AADORA1HDAC6FAAH | |
| SCHEMBL5547180 | 0.69 | SMN1; SMN2 (0.49) | ATG4BKMT2AADORA2AADORA1FAAH | |
| SCHEMBL13972703 | 0.68 | ALDH1A1 (0.57) | CYP3A4MEN1KMT2APOLBTDP1 | |
| SCHEMBL10243391 | 0.68 | CASP1 (0.45) | — | |
| SCHEMBL5176476 | 0.67 | CYP1A2 (0.48) | ATG4BCYP3A4ADORA2AADORA1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |