Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10115085 | 0.82 | ATM (0.33) | LMNA | |
| SCHEMBL13370341 | 0.79 | LMNA (0.33) | PKMTHRATHRBLMNAHTT | |
| SCHEMBL13370303 | 0.78 | PKM (0.38) | PKMTHRATHRBLMNAHTT | |
| SCHEMBL13973439 | 0.73 | SMN1; SMN2 (0.37) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL10115087 | 0.71 | ATM (0.33) | LMNA | |
| SCHEMBL12882611 | 0.69 | LMNA (0.61) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL10115195 | 0.64 | ALDH1A1 (0.40) | LMNA | |
| SCHEMBL13565178 | 0.64 | — | — | |
| SCHEMBL13973228 | 0.64 | ALDH1A1 (0.40) | LMNA | |
| SCHEMBL10114850 | 0.63 | ALDH1A1 (0.39) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |