Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13972730 | 0.79 | PKM (0.33) | LMNAHTTSMN1; SMN2PKMTHRA | |
| SCHEMBL13370303 | 0.78 | PKM (0.38) | LMNAHTTSMN1; SMN2PKMTHRA | |
| SCHEMBL13370430 | 0.64 | CA1 (0.41) | LMNAHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL13973439 | 0.63 | SMN1; SMN2 (0.37) | LMNAHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL10115085 | 0.63 | ATM (0.33) | LMNA | |
| SCHEMBL10115087 | 0.62 | ATM (0.33) | LMNA | |
| SCHEMBL28934704 | 0.60 | — | — | |
| SCHEMBL12846467 | 0.58 | MEN1 (0.35) | LMNAHTTSMN1; SMN2THRATHRB | |
| SCHEMBL8079767 | 0.57 | LMNA (0.49) | LMNAHTTSMN1; SMN2PKMTHRA | |
| SCHEMBL19847366 | 0.56 | SOAT2 (0.42) | PKMTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-B1 | NPYY5 antagonists | SHIONOGI & CO (JP) | 2010-05-05 | — | — | EP | disclosed |