Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8278009 | 0.89 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL8279674 | 0.89 | CHRM2 (0.68) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL31105715 | 0.89 | CHRM2 (0.68) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL13973181 | 0.88 | ALDH1A1 (0.58) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL13973310 | 0.86 | ALDH1A1 (0.57) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL13948896 | 0.84 | ALDH1A1 (0.70) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL18664526 | 0.83 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL13973034 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL24061766 | 0.82 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL327459 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | ANGION BIOMEDICA CORPORATION (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058312-A1 | Modulators of hepatocyte growth factor/c-Met activity | HGF, MET, HDGF | KDM4E 2380/4885ALDH1A1 823/4885SMN1; SMN2 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.